Any half-decent GUI should cover everything shown in this cheatsheet. You’d have to do quite some voodoo witchcraft to need CLI these days. It’s actually the reverse sometimes, when my terminal bretheren complain that I do too much witchcraft when I’m just tidying stuff up with a GUI.
Nope. I’ve had a script with almost 100 regex’s that automatically blacklisted around 200 people every time I opened Twitter. Two years in and upwards of 300.000 accounts in the blacklist, I realized that it didn’t even make a dent in dealing with all of the spam I was seeing, and just deleted my account. Best decision ever. I advice you too, to try it out.