When traveling or socializing we have less control of our food quality and preparation. What Carnivore options do you choose when your out?

  • jet@hackertalks.comOPMEnglish
    21·
    5 months ago

    Can you please cite direct sources? All the papers I’ve read indicate the opposite

    Saturated fats have definitely been associated with insulin resistance

    What is the mechanism is this? How does fat increase insulin resistance? Fat does not trigger a insulin response.

    • ProfessorOwl_PhD [any]@hexbear.netEnglish
      2·
      5 months ago

      Well the most famous I know of is the Kanwu Study

      How does fat increase insulin resistance? Fat does not trigger a insulin response.

      Insulin regulates your metabolism and the conversion between sugars and fats within your body, affecting everything from sugar production to protein synthesis. Your body isn’t a simple mechanism where everything has one job and is unaffected by the rest of the chemical soup. Fats don’t trigger a release of insulin, that doesn’t mean they have no effect on it.

      • jet@hackertalks.comOPMEnglish
        1·
        5 months ago

        Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity

        Thank you for the reference, it was a interesting read. This study has the Saturated fat group at 50% saturated fat, and 50% unsaturated fats, its not a very clean signal. I’m not sure why the SAFA group had a reduced response to a GTT, it warrants further study.

        Since the study you reference is from 2001, there are more recent studies that reference it.

        https://www.sciencedirect.com/science/article/pii/S2161831323000674

        Saturated Fatty Acid Intake and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Cohort Studies

        There was evidence of publication bias among studies on dietary total SFAs and T2DM. Our results indicated no significant association between dietary total SFA and risk of T2DM.

        Some of the experimental studies support the notion that dietary fats, and SFAs in particular, are associated with the development of insulin resistance and type 2 diabetes mellitus (T2DM) (2–5). On the other hand, the majority of more recent cohort studies have indicated no association between dietary SFAs and the incidence of T2DM

        The linear dose–response meta-analysis of the main 13 studies showed no linear association between increasing intake of SFAs and T2DM risk (HR: 0.93; 95% CI: 0.84, 1.03). From 13 cohort studies regarding the association between total SFAs and T2DM risk, 7 studies (5–7, 9, 31, 33, 34) reported sufficient data for the nonlinear doseresponse analyses. There was no evidence of a U- or J-shaped association between total SFA intake and risk of T2DM (Pnonlinearity = 0.153; n = 7; Figure 3). Supplemental Figure 5 presents the results for publication bias. Overall, there was evidence of publication bias with the Egger test (P = 0.032).