There should be a config file in ~/.config/MangoHud
(you can check more details in the GitHub page https://github.com/flightlessmango/MangoHud#hud-configuration).
By adding frametime=0
to the config file, you should be able to remove the frametime measurement from the FPS display.
I get the same errors about descriptor, but no mention of mlt or missing libraries.
I tried the flatpak version and that seems to be working.